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  • HIV-1: What It Is and What You Need to Know

    2017-3-19 · HIV-1一种能攻击人体内脏系统的病毒。. 它把 人体免疫系统 中最重要的T4淋巴组织作为攻击目标,大量破坏T4淋巴组织,产生高致命性的内衰竭。. 这种病毒在地域内终生传染,破坏人的免疫平衡,使人体成为各种疾病的载体。. HIV-1身并不会引发任何疾病,而是当免疫系统被HIV破坏后,人体由于抵抗能力过低,丧失复制免疫细胞的机会,从而感染其他的疾病导致各种 ...

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  • HIV-1 infection activates endogenous retroviral

    2021-3-24 · HIV-1 is a type of retrovirus that originated from a similar virus in chimpanzees. It’s believed that this virus was passed to humans when they came into contact with the blood of chimpanzees ...

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  • HIV-1 | definition of HIV-1 by Medical dictionary

    HIV-1: AIDS-related virus–ARV, Human immunodeficiency virus, human T-cell lymphotrophic virus, type III–HTLV-III, lymphadenopathy-associated virus–LAV The retrovirus intimately linked to AIDS Skin in HIV See HIV dermatopathy Diagnosis PCR, ELISA to screen for anti-HIV IgM antibodies; ELISA-positive sera is subjected to Western immunoblot ...

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  • HIV-1 vs. HIV-2: Differences and similarities

    2014-4-9 · 中国HIV-1基因亚型分布及流行趋势 Distribution of HIV-1 genotypes in China:a systematic review 收稿日期:2014-04-09 出版日期:2014-09-15 DOI: 10.3760/cma.j.issn.0254-6450.2014.10.020 中文关键词: 人类免疫缺陷病毒-1;基因型;系统综述 英文关键词: HIV-1

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  • HIV-1 subtypes | aidsmap

    2018-12-8 · 对HIV-1进行持续的分子流行病学监测对于HIV-1疫苗的开发以及保持HIV-1诊断和病毒载量检测的准确性仍然至关重要。” 在全球范围内,在2010年至2015年,HIV-1亚型C占所有HIV-1感染的将近一半(46.6%)。 HIV-1亚型B导致12.1%的感染,HIV-1亚型A导致10

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  • HIV-1 reverse transcription - PubMed

    Reverse transcription and integration are the defining features of the Retroviridae; the common name 'retrovirus' derives from the fact that these viruses use a virally encoded enzyme, reverse transcriptase (RT), to convert their RNA genomes into DNA. Reverse transcription is an essential step in re …

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  • HIV-1 vs. HIV-2: Differences and similarities

    2016-12-7 · 最好像这个图一样

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  • HIV/AIDS - World Health Organization

    2020-6-3 · 一些来自HIV-1包膜糖蛋白的多肽 (Env, gp120-gp41)已被证明可以有效抑制HIV-1感染。. 近日来自复旦大学、北京协和医学院、河北农业大学和中科院生物物理研究所等单位的研究人员从HIV包膜蛋白中筛选了一个肽库,以寻找能够抑制病毒的肽,相关研究成果于近日 ...

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  • HIV-1 assembly, release and maturation | Nature

    2015-6-29 · HIV-1 is the causative agent of AIDS, one of the most devastating viral pandemics in history. Although effective treatments are available to suppress HIV-1 replication in infected patients ...

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  • HIV-1 reverse transcription - PubMed

    Reverse transcription and integration are the defining features of the Retroviridae; the common name 'retrovirus' derives from the fact that these viruses use a virally encoded enzyme, reverse transcriptase (RT), to convert their RNA genomes into DNA. Reverse transcription is an essential step in re …

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  • Targeting mitochondria to beat HIV-1 | Nature

    2021-3-25 · HIV-1 infection of CD4+ T cells triggers the interaction of the mitochondrial proteins NLRX1 and FASTKD5 to promote oxidative phosphorylation, leading to increased viral replication. It has now ...

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  • HIV Types and Strains - WebMD

    2017-11-22 · HIV-1的病毒核心蛋白具有较好的免疫原性,是HIV最保守的蛋白之一。 env基因编码病毒包膜蛋白, gp160是HIV包膜糖蛋白前体。 该前体蛋白在蛋白酶的作用下被切割成外膜蛋白gp120和跨膜蛋 …

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  • What Is the Difference Between HIV-1 and HIV-2?

    2021-7-8 · There are two main types of human immunodeficiency virus (HIV) -- HIV-1 and HIV-2.Both can lead to AIDS. However, they're very different from each other. HIV-1 is the most common type.

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  • HIV/AIDS - World Health Organization

    2020-8-7 · HIV-1 is the most common type of HIV and accounts for 95% of all infections, whereas HIV-2 is relatively uncommon and less infectious. HIV-2 is mainly concentrated in West Africa and the surrounding countries. HIV-2 is less fatal and progresses more slowly than HIV-1. Currently, only one antibody test can distinguish between antibodies to HIV-1 ...

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  • About HIV-1 Interactions - National Institutes of Health

    The HIV-1, human interactions project collates published reports of two types of interactions - protein interactions, and human gene knock-downs that affect virus replication and infectivity (reported as 'replication interactions'). Documenting the interaction of human immunodeficiency virus type 1 (HIV-1) with the host cell is crucial to ...

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  • HIV-1 Interactions Database - National Institutes of

    2014-7-25 · Search criteria Interaction type Protein Replication Both Gene Ontology (GO) Protein domain name Properties Has phenotype Has gene expression data Has Homologene Cluster Has >1 …

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  • Cone-shaped HIV-1 capsids are transported through

    2021-2-18 · Introduction. Human immunodeficiency virus type 1 (HIV-1) is a lentivirus that infects non-dividing cells (Yamashita and Emerman, 2006).The primary targets of HIV-1 in vivo are immune cells, including CD4 + T lymphocytes and macrophages (Stevenson, 2003).Five and seven CA pentamers incorporated at the narrow and broad end of the cone, respectively, close the capsid and induce the ...

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  • PSGL-1 restricts HIV-1 infectivity by blocking virus ...

    2010-12-28 · HIV-1病毒有着非常复杂的表达调控系统,序列分析显示HIV-1结构基因的表达主要通过HIV-1 5’LTR的U3和R区的启动元件以及pol基因的内部启动子来控制[1]。HIV-1 LTR的U3和R区包含了四个功能区域:调节区、增强子单位、核心启动子单位、Tat反应原件。

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  • FOXO1 transcription factor plays a key role in T

    HIV-1 infection, or expression of either Vpu or Nef, down-regulates PSGL-1 from the cell surface; expression of Vpu appears to be primarily responsible for enabling the virus to partially escape PSGL-1-mediated restriction. Finally, we show that PSGL-1 inhibits the infectivity of other viruses, such as murine leukemia virus and influenza A virus.

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  • HIV Types and Strains - WebMD

    2019-5-1 · Abstract. HIV-1 is dependent on the host cell for providing the metabolic resources for completion of its viral replication cycle. Thus, HIV-1 replicates efficiently only in activated CD4 + T cells. Barriers preventing HIV-1 replication in resting CD4 + T cells include a block that limits reverse transcription and also the lack of activity of several inducible transcription factors, such as NF ...

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  • What Is the Difference Between HIV-1 and HIV-2?

    2021-7-8 · There are two main types of human immunodeficiency virus (HIV) -- HIV-1 and HIV-2.Both can lead to AIDS. However, they're very different from each other. HIV-1 is the most common type.

    Get Price
  • HIV/AIDS - WHO | World Health Organization

    2020-8-7 · HIV-1 is the most common type of HIV and accounts for 95% of all infections, whereas HIV-2 is relatively uncommon and less infectious. HIV-2 is mainly concentrated in West Africa and the surrounding countries. HIV-2 is less fatal and progresses more slowly than HIV-1. Currently, only one antibody test can distinguish between antibodies to HIV-1 ...

    Get Price
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